To Downtown St. Catharines

From Toronto:

Queen Elizabeth Highway (QEW) in the direction of Niagara Falls. Follow the Queen Elizabeth Way around the lake, then Southeast to St. Catharines.

At Exit 49, turn onto Highway 406 south and continue until you reach the Fourth Avenue Exit (the first exit)

Turn left onto Fourth Avenue, proceed up the hill, and turn right at the first intersection at Ontario Street. 

Follow Ontario Street up to St. Paul Street (about four stop lights)

Turn left onto St. Paul Street.. The Niagara Artist's Centre is at 354 St. Paul, on the right, just past Bond Street,

just past the Ministry of Transporation Building. 

Parking Tips: Most of the spots on St. Paul Street,  near the NAC will be taken. If you don't mind walking a block or two on  a summer's evening , you can park on of the nearby streets (King, James, Court, Church) or use one of the city owned parking lots (corner of King and Garden Park, Raymond at Church, Behind the Library off Carlise, the Ontario Street Parking garage (near St. Paul) and Market Square (James between Church and King St.) Here is a list of lots and fees:

http://www.stcatharines.ca/cityservices/citydepartments/fms/resources/07parkingratesREV.pdf